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Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (C-Term), (AA 709-738) antibody

Details for Product No. ABIN654881
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Antigen
Synonyms NRF1, LCR-F1, TCF11, AA408798, AW212678, Lcrf1, TCF-11
Epitope
C-Term, AA 709-738
(11), (8), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(24), (7), (3), (1), (1)
Host
Rabbit
(20), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(25), (11)
Pubmed 4 references available
Quantity 400 µL
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Catalog No. ABIN654881
291.50 $
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Immunogen This NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 709-738 AA from the C-terminal region of human NFE2L1.
Clone RB27999
Isotype Ig
Specificity This NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 712-742 amino acids from the C-terminal region of human NFE2L1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NFE2L1
Background This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
Synonyms: Nuclear factor erythroid 2-related factor 1,NFE2L1,HBZ17, NRF1, TCF11
Molecular Weight 84704 DA
Gene ID 4779
UniProt NP_003195.1, Q14494
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) (C-Term), (AA 709-738) antibody NFE2L1 Antibody (C-term) (ABIN654881) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the NFE2L1 antibody detected the NFE2L1 protein (arrow).
Background publications Newman, Keating: "Comprehensive identification of human bZIP interactions with coiled-coil arrays." in: Science (New York, N.Y.), Vol. 300, Issue 5628, pp. 2097-101, 2003 (PubMed).

Wang, Kwok, Chan: "The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 24670-8, 2007 (PubMed).

Radhakrishnan, Lee, Young et al.: "Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells." in: Molecular cell, Vol. 38, Issue 1, pp. 17-28, 2010 (PubMed).

Steffen, Seeger, Koch et al.: "Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop." in: Molecular cell, Vol. 40, Issue 1, pp. 147-58, 2010 (PubMed).

Validation Images
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