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Details for Product No. ABIN655818

Interferon Regulatory Factor 9 (IRF9) (N-Term), (AA 75-104) antibody

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Antigen
Synonyms p48, IRF-9, ISGF3, ISGF3G, Irf-9, Isgf3g, zgc:92097
Epitope
»Alternatives N-Term, AA 75-104
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN655818
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 AA from the N-terminal region of human IRF9.
Clone RB19229
Isotype Ig
Specificity This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the N-terminal region of human IRF9.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IRF9
Background IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Synonyms: Interferon regulatory factor 9,IRF9,ISGF3G
Molecular Weight 43696 DA
Gene ID 10379
UniProt Q00978, NP_006075
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Alternatives for antigen "Interferon Regulatory Factor 9 (IRF9)", type "Antibodies"
Hosts (15), (8), (1)
Reactivities (23), (6), (1), (1), (1), (1), (1)
Applications (24), (11), (9), (9), (8), (3), (2), (1), (1)
Epitopes (5), (5), (2), (1), (1), (1)
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