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Details for Product No. ABIN655886

RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) (AA 217-244), (Center) antibody

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Antigen
Synonyms BC011279, GDS1, SmgGDS, XsmgGDS, gds1, rap1gds1, smgGDS
Epitope
»Alternatives AA 217-244, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN655886
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This RAP1GDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 AA from the Central region of human RAP1GDS1.
Clone RB31690
Isotype Ig
Specificity This RAP1GDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-252 amino acids from the Central region of human RAP1GDS1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RAP1GDS1
Background The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).
Synonyms: Rap1 GTPase-GDP dissociation stimulator 1,RAP1GDS1,
Molecular Weight 66317 DA
Gene ID 5910
UniProt NP_001093900.1, P52306
Research Area Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: IHC : 1:10-50,WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Tiwari, Felekkis, Moon et al.: "Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis." in: Blood, Vol. 103, Issue 7, pp. 2661-7, 2004 (PubMed).

Branham, Bustos, De Blas et al.: "Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis." in: The Journal of biological chemistry, Vol. 284, Issue 37, pp. 24825-39, 2009 (PubMed).

Schönherr, Yang, Vigny et al.: "Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells." in: Oncogene, Vol. 29, Issue 19, pp. 2817-30, 2010 (PubMed).

Alternatives for antigen "RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1)", type "Antibodies"
Hosts (22), (1)
Reactivities (23), (14), (12), (2)
Applications (13), (10), (6), (6), (4), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (2), (2), (1), (1)
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