Integrator Complex Subunit 1 (INTS1) (N-Term), (AA 113-142) antibody

Details for Product No. ABIN656190
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Antigen
Epitope
N-Term, AA 113-142
(10), (2), (1)
Reactivity
Human
(13)
Host
Rabbit
(13)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(13), (7), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN656190
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Immunogen This INTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 AA from the N-terminal region of human INTS1.
Clone RB09659
Isotype Ig
Specificity This INTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human INTS1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name INTS1
Background INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
Synonyms: INTS1,Integrator complex subunit 1,KIAA1440
Molecular Weight 244297 DA
Gene ID 26173
NCBI Accession NP_001073922
UniProt Q8N201
Research Area Signaling, Phospho-specific antibodies, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment INTS1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Integrator Complex Subunit 1 (INTS1) (N-Term), (AA 113-142) antibody INTS1 Antibody (ABIN656190) western blot analysis in human placenta tissue lysates (35 µg/lane). This demonstrates the INTS1 antibody detected the INTS1 protein (arrow).
Background publications Baillat, Hakimi, Näär et al.: "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II." in: Cell, Vol. 123, Issue 2, pp. 265-76, 2005 (PubMed).

Nusbaum, Mikkelsen, Zody et al.: "DNA sequence and analysis of human chromosome 8." in: Nature, Vol. 439, Issue 7074, pp. 331-5, 2006 (PubMed).

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