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Details for Product No. ABIN656260

Dishevelled, Dsh Homolog 1 (Drosophila) (DVL1) (AA 442-470), (Center) antibody

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Antigen
Synonyms DVL, DVL1L1, DVL1P1, Dvl, mKIAA4029, dvl-1, dvl1, dvl2l, Xdsh, dsh1, DSH, DVL-1, dvl3, wu:fb75f04, wu:fi22h02, wu:fp61b09, dsh3, DVL1
Epitope
»Alternatives AA 442-470, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 1 reference available
Catalog no. ABIN656260
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 AA from the Central region of human DVL1.
Clone RB31716
Isotype Ig
Specificity This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from the Central region of human DVL1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DVL1
Background DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Synonyms: DVL1,Segment polarity protein dishevelled homolog DVL-1,
Pathways: Wnt signaling pathway, Melanogenesis, Basal cell carcinoma
Molecular Weight 75187 Da
Gene ID 1855
UniProt O14640
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.46 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Varelas, Miller, Sopko et al.: "The Hippo pathway regulates Wnt/beta-catenin signaling." in: Developmental cell, Vol. 18, Issue 4, pp. 579-91, 2010 (PubMed).

Alternatives for antigen "Dishevelled, Dsh Homolog 1 (Drosophila) (DVL1)", type "Antibodies"
Hosts (22), (3), (2)
Reactivities (22), (19), (17), (4), (3), (3), (1), (1), (1), (1), (1), (1)
Applications (18), (10), (8), (5), (4), (3), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (2), (2), (1), (1), (1), (1), (1)
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