anti-DVL1 antibody (Dishevelled, Dsh Homolog 1 (Drosophila)) (AA 442-470)

Details for Product anti-DVL1 Antibody No. ABIN656260
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AA 442-470, Center
(18), (14), (12), (9), (9), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1)
(49), (30), (18), (11), (4), (2), (1), (1), (1)
(48), (20), (3)
Clonality (Clone)
Polyclonal ()
This DVL1 antibody is un-conjugated
(7), (7), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(58), (39), (17), (10), (8), (6), (3), (3), (1)
Pubmed 1 reference available
Quantity 400 μL
Shipping to United States ( )
Availability Please contact our customer support.
Immunogen This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-470 AA from the Central region of human DVL1.
Clone RB31716
Isotype Ig
Specificity This DVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from the Central region of human DVL1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DVL1 (DVL1 Antibody Abstract)
Background DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Synonyms: DVL1,Segment polarity protein dishevelled homolog DVL-1,
Pathways: Wnt signaling pathway, Melanogenesis, Basal cell carcinoma
Molecular Weight 75187 Da
Gene ID 1855
UniProt O14640
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways WNT Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.46 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Image no. 1 for anti-DVL1 antibody (Dishevelled, Dsh Homolog 1 (Drosophila)) (AA 442-470) (ABIN656260) Confocal immunofluorescent analysis of DVL1 Antibody (Center) (ABIN656260) with HepG2...
Background publications Varelas, Miller, Sopko et al.: "The Hippo pathway regulates Wnt/beta-catenin signaling." in: Developmental cell, Vol. 18, Issue 4, pp. 579-91, 2010 (PubMed).

Catalog No. ABIN656260
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