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IGSF8 antibody (Immunoglobulin Superfamily, Member 8) (AA 226-254)

Details for Product anti-IGSF8 Antibody No. ABIN656323, Supplier: Login to see
Antigen
  • MGC77222
  • IGSF8
  • MGC151661
  • CD316
  • CD81P3
  • EWI-2
  • EWI2
  • KCT-4
  • LIR-D1
  • PGRL
  • AA033172
  • AU041109
  • ESTM34
  • R75384
Epitope
AA 226-254, Center
22
16
13
9
3
3
2
2
2
1
1
1
1
Reactivity
Mouse (Murine)
55
34
21
2
2
2
2
1
1
1
1
1
Host
Rabbit
58
6
Clonality (Clone)
Polyclonal ()
Conjugate
This IGSF8 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
27
19
12
11
2
1
1
Supplier
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Immunogen This IGSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 AA from the Central region of human IGSF8.
Clone RB31348
Isotype Ig
Specificity This IGSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the Central region of human IGSF8.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IGSF8 (IGSF8 Antibody Abstract)
Background IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
Synonyms: IGSF8,Immunoglobulin superfamily member 8,CD81P3, EWI2, KCT4
Molecular Weight 65034 DA
Gene ID 93185
NCBI Accession NP_443100
UniProt Q969P0
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.39 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment IGSF8 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-IGSF8 antibody (Immunoglobulin Superfamily, Member 8) (AA 226-254) (ABIN656323) IGSF8 Antibody (Center) (ABIN656323) immunohistochemistry analysis in formalin fixed ...
Background publications Kolesnikova, Kazarov, Lemieux et al.: "Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 1, pp. 77-86, 4p following 86, 2008 (PubMed).

Yang, Kovalenko, Kolesnikova et al.: "Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization." in: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12976-85, 2006 (PubMed).