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Details for Product No. ABIN656327

delta Like Protein 3 (DLL3) (C-Term), (AA 545-573) antibody

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Synonyms pu, pudgy, SCDO1
»Alternatives C-Term, AA 545-573
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 3 references available
Catalog no. ABIN656327
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 545-573 AA from the C-terminal region of human DLL3.
Clone RB31357
Isotype Ig
Specificity This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 552-583 amino acids from the C-terminal region of human DLL3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DLL3
Background This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].
Synonyms: DLL3,Delta-like protein 3,
Molecular Weight 64618 DA
Gene ID 10683
UniProt NP_058637.1, Q9NYJ7, NP_982353.1
Research Area Ubiquitin-related antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cell Cycle
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DLL3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Bonafé, Giunta, Gassner et al.: "A cluster of autosomal recessive spondylocostal dysostosis caused by three newly identified DLL3 mutations segregating in a small village." in: Clinical genetics, Vol. 64, Issue 1, pp. 28-35, 2003 (PubMed).

Whittock, Ellard, Duncan et al.: "Pseudodominant inheritance of spondylocostal dysostosis type 1 caused by two familial delta-like 3 mutations." in: Clinical genetics, Vol. 66, Issue 1, pp. 67-72, 2004 (PubMed).

Maisenbacher, Han, Obrien et al.: "Molecular analysis of congenital scoliosis: a candidate gene approach." in: Human genetics, Vol. 116, Issue 5, pp. 416-9, 2005 (PubMed).

Alternatives for antigen "delta Like Protein 3 (DLL3)", type "Antibodies"
Hosts (26), (1)
Reactivities (25), (14), (12), (12), (2), (1)
Applications (18), (9), (7), (7), (7), (5), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (2), (2), (2), (2), (2), (1), (1), (1)