Ribonuclease P/MRP 38kDa Subunit (RPP38) (C-Term), (AA 248-277) antibody

Details for Product No. ABIN656669
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Antigen
Synonyms MGC81745, RPP38, C330006A15Rik
Epitope
C-Term, AA 248-277
(8), (8), (1), (1)
Reactivity
Human
(13), (3), (3)
Host
Rabbit
(12), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(13), (10)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN656669
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Immunogen This RPP38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 AA from the C-terminal region of human RPP38.
Clone RB32415
Isotype Ig
Specificity This RPP38 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-283 amino acids from the C-terminal region of human RPP38.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RPP38
Background Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus.
Synonyms: Ribonuclease P protein subunit p38,RPP38,
Molecular Weight 31834 DA
Gene ID 10557
UniProt NP_001091059.1, NP_006405.2, NP_892117.1, P78345
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment RPP38 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Ribonuclease P/MRP 38kDa Subunit (RPP38) (C-Term), (AA 248-277) antibody RPP38 Antibody (C-term) (ABIN656669) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the RPP38 antibody detected the RPP38 protein (arrow).
Background publications Welting, van Venrooij, Pruijn: "Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex." in: Nucleic acids research, Vol. 32, Issue 7, pp. 2138-46, 2004 (PubMed).

Andersen, Lam, Leung et al.: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, 2005 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Validation Images
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