Double C2-Like Domains, alpha (DOC2A) (AA 277-306), (Center) antibody

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Synonyms Doc2, DOC2A, doc2-A
AA 277-306, Center
(2), (2), (2), (1), (1), (1), (1)
(11), (1), (1), (1), (1)
(6), (4), (1)
Clonality (Clone)
Polyclonal ()
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC)
(7), (6), (2), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN656766
Quantity 400 µL
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Immunogen This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 AA from the Central region of human DOC2A.
Clone RB32573
Isotype Ig
Specificity This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the Central region of human DOC2A.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DOC2A
Background There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Synonyms: Double C2-like domain-containing protein alpha,DOC2A,
Molecular Weight 43959 DA
Gene ID 8448
UniProt Q14183, NP_003577.2
Research Area Cell Structure, Neurology
Application Notes FACS = 1:10-50, WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DOC2A Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Double C2-Like Domains, alpha (DOC2A) (AA 277-306), (Center) antibody DOC2A Antibody (Center) (ABIN656766) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Glessner, Reilly, Kim et al.: "Strong synaptic transmission impact by copy number variations in schizophrenia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 23, pp. 10584-9, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Hosts (6), (4), (1)
Reactivities (11), (1), (1), (1), (1)
Applications (7), (6), (2), (2), (1), (1)
Epitopes (2), (2), (2), (1), (1), (1), (1)
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