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Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 316-345), (C-Term) antibody

Details for Product No. ABIN656815, Supplier: Login to see
Antigen
  • ba46
  • edil1
  • oacgd3s
  • MGC75581
  • hst19888
  • MGC145109
  • MFGE8
  • mfge8
  • zgc:154157
  • MGC99228
  • BA46
  • EDIL1
  • HMFG
  • HsT19888
  • MFG-E8
  • MFGM
  • OAcGD3S
  • SED1
  • SPAG10
  • hP47
  • AA408458
  • AI325141
  • Mfgm
  • P47
  • lactadherin
  • AGS
  • MFGME8
  • MFGMP-E8
Epitope
AA 316-345, C-Term
13
10
7
6
4
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Human
101
15
3
3
Host
Rabbit
72
38
2
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
10
8
8
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
86
42
32
23
20
17
11
10
10
7
4
2
1
Supplier
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Immunogen This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 AA from the C-terminal region of human HMFG.
Clone RB19529
Isotype Ig
Specificity This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-345 amino acids from the C-terminal region of human HMFG.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HMFG (MFGE8 Antibody Abstract)
Background HMFG plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.
Synonyms: Lactadherin,MFGE8,
Molecular Weight 43123 DA
Gene ID 4240
NCBI Accession NP_001108086, NP_005919
UniProt Q08431
Research Area Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment HMFG Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (AA 316-345), (C-Term) antibody (ABIN656815) HMFG Antibody (C-term) (ABIN656815) western blot analysis in Hela cell line lysates (...
Background publications Yamaguchi, Fujimoto, Nakamura et al.: "Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus." in: European journal of immunology, Vol. 40, Issue 6, pp. 1778-85, 2010 (PubMed).

Wheeler, Metter, Tanaka et al.: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).