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Details for Product No. ABIN656815

Milk Fat Globule-EGF Factor 8 Protein (MFGE8) (C-Term), (AA 316-345) antibody

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BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47, AA408458, AI325141, Mfgm, P47, lactadherin, AGS, MFGME8, MFGMP-E8, ba46, edil1, oacgd3s, MGC75581, hst19888, MGC145109, MFGE8, m ... show more
»Alternatives C-Term, AA 316-345
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN656815
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 AA from the C-terminal region of human HMFG.
Clone RB19529
Isotype Ig
Specificity This HMFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-345 amino acids from the C-terminal region of human HMFG.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HMFG
Background HMFG plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication. Medin is the main constituent of aortic medial amyloid.
Synonyms: Lactadherin,MFGE8,
Molecular Weight 43123 DA
Gene ID 4240
UniProt Q08431, NP_005919.2, NP_001108086.1
Research Area Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment HMFG Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Wheeler, Metter, Tanaka et al.: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).

Yamaguchi, Fujimoto, Nakamura et al.: "Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus." in: European journal of immunology, Vol. 40, Issue 6, pp. 1778-85, 2010 (PubMed).

Alternatives for antigen "Milk Fat Globule-EGF Factor 8 Protein (MFGE8)", type "Antibodies"
Hosts (28), (22), (2), (2)
Reactivities (49), (4)
Applications (42), (25), (18), (18), (11), (10), (5), (5), (4), (3), (3), (1), (1), (1)
Conjugates (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (3), (2), (1)