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La Ribonucleoprotein Domain Family, Member 7 (LARP7) (C-Term), (AA 527-556) antibody

Details for Product No. ABIN656914
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Antigen
Synonyms ALAZS, PIP7S, D3Wsu161e, C330027G06Rik, fa10g04, zgc:56476, wu:fa10g04, LARP7
Epitope
C-Term, AA 527-556
(6), (2), (1), (1), (1)
Reactivity
Human
(11), (6), (5), (2), (2), (2), (1)
Host
Rabbit
(16)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1)
Application
Western Blotting (WB)
(13), (4), (3)
Pubmed 3 references available
Catalog no. ABIN656914
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 AA from the C-terminal region of human LARP7.
Clone RB32547
Isotype Ig
Specificity This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of human LARP7.
Predicted Reactivity Mouse (Murine),Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LARP7
Background LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Synonyms: La-related protein 7,LARP7,
Molecular Weight 66899 DA
Gene ID 51574
UniProt NP_056269.1, NP_057732.2, Q4G0J3
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment LARP7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-La Ribonucleoprotein Domain Family, Member 7 (LARP7) (C-Term), (AA 527-556) antibody LARP7 Antibody (C-term) (ABIN656914) western blot analysis in WiDr cell line lysates (35 µg/lane). This demonstrates the LARP7 antibody detected the LARP7 protein (arrow).
Background publications He, Jahchan, Hong et al.: "A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis." in: Molecular cell, Vol. 29, Issue 5, pp. 588-99, 2008 (PubMed).

Kalsi, Kuo, Aliev et al.: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, 2010 (PubMed).

Tyagi, Pearson, Karn: "Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction." in: Journal of virology, Vol. 84, Issue 13, pp. 6425-37, 2010 (PubMed).

Hosts (16)
Reactivities (11), (6), (5), (2), (2), (2), (1)
Applications (13), (4), (3)
Conjugates (1), (1)
Epitopes (6), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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