PACS2 antibody (C-Term)

Catalog No. ABIN657066

Product Details anti-PACS2 Antibody

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Binding Specificity: AA 642-671, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PACS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642-671 amino acids from the C-terminal region of human PACS2.

Clone: RB32549

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PACS2

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Alternative Name: PACS2 (PACS2 Products)

Synonyms: PACS-2 antibody, PACS1L antibody, 6720425G15Rik antibody, AW208651 antibody, AW489976 antibody, E230011J22 antibody, Pacs1l antibody, mKIAA0602 antibody, phosphofurin acidic cluster sorting protein 2 antibody, PACS2 antibody, Pacs2 antibody

Background: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Molecular Weight: 97702

NCBI Accession: NP_001094383, NP_001230056, NP_056012

UniProt: Q86VP3