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Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2) (AA 152-180), (N-Term) antibody

Details for Product No. ABIN657382, Supplier: Log in to see
Antigen
  • rab2l
  • im:7136742
  • Ke1.5
  • Rab2l
  • RGL2
  • MGC139909
  • HKE1.5
  • KE1.5
  • RAB2L
  • Rgt2
  • Rlf
Epitope
AA 152-180, N-Term
15
14
7
4
2
1
Reactivity
Human
29
Host
Rabbit
17
12
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
28
18
4
1
1
Supplier
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Immunogen This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 AA from the N-terminal region of human RGL2.
Clone RB33009
Isotype Ig
Specificity This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human RGL2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RGL2 (RGL2 Antibody Abstract)
Background Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
Synonyms: Ral guanine nucleotide dissociation stimulator-like 2,RGL2,RAB2L
Molecular Weight 83549 DA
Gene ID 5863
NCBI Accession NP_004752
UniProt O15211
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment RGL2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2) (AA 152-180), (N-Term) antibody (ABIN657382) RGL2 Antibody (N-term) (ABIN657382) western blot analysis in uterine tumor cell line ...
Background publications Vigil, Martin, Williams et al.: "Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34729-40, 2010 (PubMed).

Barcellos, May, Ramsay et al.: "High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000696, 2009 (PubMed).

Ferro, Magrini, Guazzi et al.: "G-protein binding features and regulation of the RalGDS family member, RGL2." in: The Biochemical journal, Vol. 415, Issue 1, pp. 145-54, 2008 (PubMed).

Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).