RGL2 antibody (AA 644-743)

Catalog No. ABIN562553

There are 2+ publications for this product available. The Mouse Monoclonal anti-RGL2 antibody is suitable to detect RGL2 in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for RGL2 antibody (AA 644-743) (ABIN562553)

Target: RGL2 (Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RGL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 4D10

Product Details anti-RGL2 Antibody

Binding Specificity: AA 644-743

Purpose: Mouse monoclonal antibody raised against a partial recombinant RGL2.

Sequence: PGASDCRIIR VQMELGEDGS VYKSILVTSQ DKAPSVISRV LKKNNRDSAV ASEYELVQLL PGERELTIPA SANVFYAMDG ASHDFLLRQR RRSSTATPGV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RGL2 (AAH32681, 644 a.a. ~ 743 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RGL2 antibody (ABIN562553)

Castro, Campos, Babcock, Armijo, Martínez-Conde, Pincheira, Quilliam: "M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells." in: Journal of cellular biochemistry, Vol. 113, Issue 4, pp. 1253-64, (2012) (PubMed).

Vigil, Martin, Williams, Yeh, Campbell, Der: "Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34729-40, (2010) (PubMed).

Target Details for RGL2

Target: RGL2 (Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2))

Alternative Name: RGL2

Background: Full Gene Name: ral guanine nucleotide dissociation stimulator-like 2
Synonyms: HKE1.5,KE1.5,RAB2L

Gene ID: 5863