Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2) (N-Term), (AA 152-180) antibody

Details for Product No. ABIN657382
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Antigen
Synonyms KE1.5, RAB2L, HKE1.5, Rlf, Rgt2, Rab2l, rab2l, im:7136742, Ke1.5, RGL2, MGC139909
Epitope
N-Term, AA 152-180
(2), (1)
Reactivity
Human
(6)
Host
Rabbit
(4), (2)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
(6), (3), (3), (1)
Pubmed 5 references available
Catalog no. ABIN657382
Quantity 400 µL
Price
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Immunogen This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 AA from the N-terminal region of human RGL2.
Clone RB33009
Isotype Ig
Specificity This RGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human RGL2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RGL2
Background Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro (By similarity).
Synonyms: Ral guanine nucleotide dissociation stimulator-like 2,RGL2,RAB2L
Molecular Weight 83549 DA
Gene ID 5863
UniProt O15211, NP_004752.1
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment RGL2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Ral Guanine Nucleotide Dissociation Stimulator-Like 2 (RGL2) (N-Term), (AA 152-180) antibody RGL2 Antibody (N-term) (ABIN657382) western blot analysis in uterine tumor cell line lysates (35 µg/lane). This demonstrates the RGL2 antibody detected the RGL2 protein (arrow).
Background publications Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Ferro, Magrini, Guazzi et al.: "G-protein binding features and regulation of the RalGDS family member, RGL2." in: The Biochemical journal, Vol. 415, Issue 1, pp. 145-54, 2008 (PubMed).

Barcellos, May, Ramsay et al.: "High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000696, 2009 (PubMed).

Vigil, Martin, Williams et al.: "Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34729-40, 2010 (PubMed).

Hosts (4), (2)
Reactivities (6)
Applications (6), (3), (3), (1)
Epitopes (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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