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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 177-206), (Center) antibody

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Synonyms 5133400O11Rik, BB115266, D7Bwg0421e, Lair-1, mLair-1, CD305, LAIR-1
AA 177-206, Center
(31), (16), (9), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
(143), (28), (16)
(85), (53), (19), (6), (3), (2)
Clonality (Clone)
Polyclonal ()
(23), (14), (11), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(104), (79), (58), (28), (14), (11), (7), (3), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 AA from the Central region of human LAIR1.
Clone RB33925
Isotype Ig
Specificity This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-206 amino acids from the Central region of human LAIR1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LAIR1 (LAIR1 Antibody Abstract)
Background The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
Synonyms: Leukocyte-associated immunoglobulin-like receptor 1,LAIR1,CD305
Molecular Weight 31412 DA
Gene ID 3903
NCBI Accession NP_002278, NP_068352
UniProt Q6GTX8
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment LAIR1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 177-206), (Center) antibody (ABIN657706) LAIR1 Antibody (Center) (ABIN657706) western blot analysis in K562 cell line lysates ...
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Brondijk, de Ruiter, Ballering et al.: "Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI." in: Blood, Vol. 115, Issue 7, pp. 1364-73, 2010 (PubMed).

Tang, Narayanan, Peruzzi et al.: "A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 9, pp. 5446-52, 2009 (PubMed).

Catalog No. ABIN657706
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