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Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 59-86), (Center) antibody

Details for Product No. ABIN657873
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Antigen
Epitope
AA 59-86, Center
(9), (7), (3), (3), (2), (1)
Reactivity
Human
(26), (10), (9), (2)
Host
Rabbit
(20), (5), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(26), (15), (5), (3), (1), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN657873
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Immunogen This VTI1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 AA from the Central region of human VTI1B.
Clone RB24568
Isotype Ig
Specificity This VTI1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human VTI1B.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VTI1B
Background V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Synonyms: Vesicle transport through interaction with t-SNAREs homolog 1B,10490,VTI1, VTI1L, VTI1L1, VTI2
Molecular Weight 26688 DA
Gene ID 10490
UniProt NP_006361.1, Q9UEU0
Research Area Signaling, Phospho-specific antibodies, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment VTI1B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 59-86), (Center) antibody VTI1B Antibody (Center) (ABIN657873) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the VTI1B antibody detected the VTI1B protein (arrow).
Background publications Martinez-Arca, Rudge, Vacca et al.: "A dual mechanism controlling the localization and function of exocytic v-SNAREs." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 9011-6, 2003 (PubMed).

Yan, Sun, McNew et al.: "Ca2+ and N-ethylmaleimide-sensitive factor differentially regulate disassembly of SNARE complexes on early endosomes." in: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18270-6, 2004 (PubMed).

Furuta, Fujita, Noda et al.: "Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1001-10, 2010 (PubMed).

Validation Images
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