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Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 79-108), (N-Term) antibody

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Synonyms kmt1a, suv39h, H3-K9-HMTase 1, KMT1A, MG44, SUV39H, AI852103, AL022883, DXHXS7466e, mIS6, RGD1565028, fe02c04, suv39h1, wu:fe02c04, zgc:101027
AA 79-108, N-Term
(48), (15), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
(90), (33), (20), (2), (2), (1), (1)
(71), (20)
Clonality (Clone)
Polyclonal ()
(6), (6), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(72), (46), (16), (11), (11), (7), (4), (2), (2), (2)
Pubmed 5 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This SUV39H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 AA from the N-terminal region of human SUV39H1.
Clone RB34028
Isotype Ig
Specificity This SUV39H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-108 amino acids from the N-terminal region of human SUV39H1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SUV39H1 (SUV39H1 Antibody Abstract)
Background This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.
Synonyms: Histone-lysine N-methyltransferase SUV39H1,6839,KMT1A, SUV39H
Molecular Weight 47907 DA
Gene ID 6839
NCBI Accession NP_003164
UniProt O43463
Research Area Translation Factors, Signaling, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SUV39H1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1) (AA 79-108), (N-Term) antibody (ABIN657943) SUV39H1 Antibody (N-term) (ABIN657943) western blot analysis in 293 cell line lysates...
Background publications Chen, Li, Zwolinska et al.: "MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output." in: The EMBO journal, Vol. 29, Issue 15, pp. 2538-52, 2010 (PubMed).

Goyama, Nitta, Yoshino et al.: "EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization." in: Leukemia, Vol. 24, Issue 1, pp. 81-8, 2010 (PubMed).

Cherrier, Suzanne, Redel et al.: "p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1." in: Oncogene, Vol. 28, Issue 38, pp. 3380-9, 2009 (PubMed).

Li, Chen, Kabra et al.: "Inhibition of SUV39H1 methyltransferase activity by DBC1." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10361-6, 2009 (PubMed).

Spensberger, Delwel: "A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a." in: FEBS letters, Vol. 582, Issue 18, pp. 2761-7, 2008 (PubMed).

Catalog No. ABIN657943
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