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SUV39H1 Products

(Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

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This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq, Jul 2008].

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Featured SUV39H1 Categories

SUV39H1 Antibodies

High quality antibodies with extensive validation data.

SUV39H1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SUV39H1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application IHC, IF
Validations
  • (6)
Cat. No. ABIN7075770
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7155525
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6265384
Quantity 100 μL
Datasheet Datasheet

Recommended SUV39H1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6207821
Quantity 96 tests
Datasheet Datasheet

Recommended SUV39H1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125258
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321937
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321936
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our SUV39H1 products

Kumari, Popescu, Yue, Bober, Ianni, Braun: "Sirt7 inhibits Sirt1-mediated activation of Suv39h1." in: Cell cycle (Georgetown, Tex.), Vol. 17, Issue 12, pp. 1403-1412, (2018) (PubMed).

Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

Spyropoulou, Gargalionis, Dalagiorgou, Adamopoulos, Papavassiliou, Lea, Piperi, Papavassiliou: "Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 70-82, (2014) (PubMed).

Sidler, Woycicki, Li, Wang, Kovalchuk, Kovalchuk: "A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts." in: Aging, Vol. 6, Issue 7, pp. 545-63, (2014) (PubMed).

Sidler, Li, Wang, Kovalchuk, Kovalchuk: "SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation." in: Frontiers in genetics, Vol. 5, pp. 411, (2014) (PubMed).

Chen, Yeh, Yang, Chang, Lee, Hung: "High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan." in: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 513, (2013) (PubMed).

Østrup, Hyttel, Klærke, Collas: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, (2011) (PubMed).

Benlhabib, Mendelson: "Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia." in: Molecular and cellular biology, Vol. 31, Issue 10, pp. 1949-58, (2011) (PubMed).

Ayrapetov, Xu, Sun, Zhu, Parmar, DAndrea, Price: "Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity." in: PLoS ONE, Vol. 6, Issue 10, pp. e26064, (2011) (PubMed).

Goyama, Nitta, Yoshino, Kako, Watanabe-Okochi, Shimabe, Imai, Takahashi, Kurokawa: "EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization." in: Leukemia, Vol. 24, Issue 1, pp. 81-8, (2010) (PubMed).

Synonyms and alternative names related to SUV39H1

suppressor of variegation 3-9 homolog 1 (SUV39H1), suppressor of variegation 3-9 homolog 1 (Drosophila) (Suv39h1), suppressor of variegation 3-9 homolog 1 L homeolog (suv39h1.L), suppressor of variegation 3-9 homolog 1a (suv39h1a), suppressor of variegation 3-9 homolog 1 (Suv39h1), suppressor of variegation 3-9 homolog 1b (suv39h1b), AI852103, AL022883, DXHXS7466e, fe02c04, fe47h06, H3-K9-HMTase 1, KMT1A, kmt1a, MG44, mIS6, RGD1565028, SUV39H, suv39h, suv39h1, wu:fb18a10, wu:fe02c04, wu:fe47h06, zgc:101027, zgc:136593

Protein level used designations for SUV39H1

  • Su(var)3-9 homolog 1
  • histone H3-K9 methyltransferase 1
  • histone-lysine N-methyltransferase SUV39H1
  • histone-lysine N-methyltransferase, H3 lysine-9 specific 1
  • lysine N-methyltransferase 1A
  • position-effect variegation 3-9 homolog
  • H3-K9-HMTase 1
  • Suv39h histone methyltransferase
  • su(var)3-9 homolog 1
  • histone-lysine N-methyltransferase SUV39H1-A
  • su(var)3-9 homolog 1-A
  • suppressor of variegation 3-9 homolog 1
  • suppressor of variegation 3-9 homolog 1-A
  • suppressor of variegation 3-9-like 1a
  • LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SUV39H1
  • suppressor of variegation 3-9-like 1b homolog 1
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