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Details for Product No. ABIN658094

Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) (MLL5) (N-Term), (AA 93-120) antibody

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Synonyms 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5, HDCMC04P, MLL5
»Alternatives N-Term, AA 93-120
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN658094
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 AA from the N-terminal region of human MLL5.
Clone RB19215
Isotype Ig
Specificity This MLL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human MLL5.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MLL5
Background This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq].
Synonyms: Histone-lysine N-methyltransferase MLL5,MLL5,KMT2E
Molecular Weight 70kd Isoform 3. 204965 DA
Gene ID 55904
UniProt NP_891847.1, NP_061152.3, Q8NFF8
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment MLL5 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Cheng, Liu, Zhou et al.: "RNA interference against mixed lineage leukemia 5 resulted in cell cycle arrest." in: The international journal of biochemistry & cell biology, Vol. 40, Issue 11, pp. 2472-81, 2008 (PubMed).

Fujiki, Chikanishi, Hashiba et al.: "GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis." in: Nature, Vol. 459, Issue 7245, pp. 455-9, 2009 (PubMed).

Liu, Wang, Cheng et al.: "Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry." in: The Journal of biological chemistry, Vol. 285, Issue 27, pp. 20904-14, 2010 (PubMed).

Alternatives for antigen "Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) (MLL5)", type "Antibodies"
Hosts (26), (2)
Reactivities (23), (18), (13), (12), (12), (12)
Applications (13), (12), (10), (9), (4), (2), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (2), (1), (1)