Order hotline:

	+1 404 474 4654
	+1 888 205 9894 (TF)

Details for Product No. ABIN783322

Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-5), (N-Term) antibody

Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms	Lin28, csdd1, lin-28, lin28, zcchc1, CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A, AL024421, ENSMUSG00000070700, Gm10299, Lin-28, Tex17, RGD1566408, sb:cb650, zgc:55584
Epitope	Alternatives AA 1-5, N-Term (12), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity	Alternatives Human, Mouse (Murine), Rat (Rattus) (51), (24), (19), (14), (14), (2), (1), (1)
Host	Alternatives Rabbit (37), (16)
Clonality	Polyclonal
Conjugate	Alternatives Un-conjugated (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application	Alternatives Western Blotting (WB) (43), (27), (12), (10), (10), (10), (5), (2), (1), (1), (1)
	3 references available

Catalog no.	ABIN783322
Quantity	0.1 mL
Price	280.50 $ Plus shipping costs $45.00

Shipping to
Availability	Will be delivered in 6 to 8 Business Days

Product details

Alternative Name	LIN28
Background	Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells. Alternate names: CSDD1, LIN-28, LIN28A, Lin-28 homolog A, ZCCHC1
Molecular Weight	26 kDa
Gene ID	79727
NCBI Accession	NP_078950
UniProt	Q9H9Z2

Alternatives for antigen "Lin-28 Homolog A (C. Elegans) (LIN28A)", type "Antibodies"

Immunogen	Peptide sequence around aa. 1~5 derived from Human Lin28
Sequence	M-G-S-V-S
Specificity	This antibody detects endogenous levels of total Lin28 protein. Species Reactivity: Tested: Human, Mouse, Rat
Purification	Affinity-chromatography using epitope-specific peptide

Format	Liquid
Concentration	1.0 mg/mL
Buffer	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Preservative	Sodium azide
Handling Advice	Avoid repeated freezing and thawing.
Storage	-20 °C
Storage Comment	Store (in aliquots) at -20 °C.
Expiry Date	12 months

Search, Find and Buy Antibodies, ELISA Kits and Proteins.
						Start help