Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1; alpha Polypeptide) (ITGAE) antibody

Antigen: Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1; alpha Polypeptide) (ITGAE)

Synonyms: CD103, HUMINAE, MGC141996, aM290, alpha-E1, MGC183601, A530055J10, alpha-M290

Clonality: Monoclonal (Ber-ACT8)

Host: Mouse

Reactivity: Human, Primate

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN810076

Additional Information

Alternative name: CD103

Gene ID: 3682

Immunogen: HTLV-1 induced human T cell line MAPS16

Isotype: IgG1

Clone: Ber-ACT8

Description: CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)

Specificity: The mouse monoclonal antibody Ber-ACT8 recognizes CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes. HLDA V, WS Code A067

Application Details

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Storage: Store at 2-8°C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles.

Research Area: CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only

Publications

Product: French, Cresswell, Wong et al.: "T cell adhesion and cytolysis of pancreatic cancer cells: a role for E-cadherin in immunotherapy?" in: British journal of cancer, Vol. 87, Issue 9, pp. 1034-41, 2002 (PubMed).

Brandes, Willimann, Lang et al.: "Flexible migration program regulates gamma delta T-cell involvement in humoral immunity." in: Blood, Vol. 102, Issue 10, pp. 3693-701, 2003 (PubMed).

Poles, Barsoum, Yu et al.: "Human immunodeficiency virus type 1 induces persistent changes in mucosal and blood gammadelta T cells despite suppressive therapy." in: Journal of virology, Vol. 77, Issue 19, pp. 10456-67, 2003 (PubMed).

León, Roy: "Isolation of human small bowel intraepithelial lymphocytes by annexin V-coated magnetic beads." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 84, Issue 6, pp. 804-9, 2004 (PubMed).

Sigmundsdottir, Johnston, Gudjonsson et al.: "Methotrexate markedly reduces the expression of vascular E-selectin, cutaneous lymphocyte-associated antigen and the numbers of mononuclear leucocytes in psoriatic skin." in: Experimental dermatology, Vol. 13, Issue 7, pp. 426-34, 2004 (PubMed).

Cardoso, Garlet, Moreira et al.: "Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis." in: Journal of leukocyte biology, Vol. 84, Issue 1, pp. 311-8, 2008 (PubMed).

Kost, Holden, Mann: "Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis." in: Cytometry. Part B, Clinical cytometry, Vol. 74, Issue 5, pp. 282-6, 2008 (PubMed).

Jaensson, Uronen-Hansson, Pabst et al.: "Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans." in: The Journal of experimental medicine, Vol. 205, Issue 9, pp. 2139-49, 2008 (PubMed).

Zhang, Bertucci, Ramsey-Goldman et al.: "Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 10, pp. 6346-58, 2009 (PubMed).