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CD103 Products

(Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Categories

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008].

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Featured CD103 Categories

CD103 Antibodies

High quality antibodies with extensive validation data.

CD103 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD103 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (5)
Cat. No. ABIN6939806
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, StM, ISt
Validations
  • (5)
Cat. No. ABIN6939807
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application FACS, WB, IP, IHC (fro)
Validations
  • (9)
  • (2)
Cat. No. ABIN810076
Quantity 0.1 mg
Datasheet Datasheet

Recommended CD103 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308179
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3122705
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3097572
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CD103 products

Böttcher, Bonavita, Chakravarty, Blees, Cabeza-Cabrerizo, Sammicheli, Rogers, Sahai, Zelenay, Reis e Sousa: "NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control." in: Cell, Vol. 172, Issue 5, pp. 1022-1037.e14, (2019) (PubMed).

Sung, Ge, Dai, Wang, Fu, Sharma, Hahn, Yu, Le, Okusa, Bolton, Lawler: "Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 7, pp. 2589-2601, (2017) (PubMed).

Cheng, Gu, Zhang, Yuan, Zhao, Jiang, Jia: "Astragaloside IV inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-?-ERK1/2-NF-?B pathway." in: International immunopharmacology, Vol. 23, Issue 1, pp. 304-13, (2015) (PubMed).

Zhang, Bertucci, Ramsey-Goldman, Burt, Datta et al.: "Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 10, pp. 6346-58, (2009) (PubMed).

Jaensson, Uronen-Hansson, Pabst, Eksteen, Tian, Coombes, Berg, Davidsson, Powrie, Johansson-Lindbom, Agace: "Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans." in: The Journal of experimental medicine, Vol. 205, Issue 9, pp. 2139-49, (2008) (PubMed).

Cardoso, Garlet, Moreira, Júnior, Rossi, Silva: "Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis." in: Journal of leukocyte biology, Vol. 84, Issue 1, pp. 311-8, (2008) (PubMed).

Kost, Holden, Mann: "Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis." in: Cytometry. Part B, Clinical cytometry, Vol. 74, Issue 5, pp. 282-6, (2008) (PubMed).

Ling, Dulphy, Bahl, Salio, Maskell, Piris, Warren, George, Mortensen, Cerundolo: "Modulation of CD103 expression on human colon carcinoma-specific CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 5, pp. 2908-15, (2007) (PubMed).

Synonyms and alternative names related to CD103

integrin alpha E, epithelial-associated (Itgae), integrin subunit alpha E (Itgae), integrin subunit alpha E (ITGAE), A530055J10, alpha-E1, alpha-M290, aM290, CD103, HUMINAE

Protein level used designations for CD103

  • integrin alpha M290
  • integrin alpha-E
  • integrin alpha E1, epithelial-associated
  • integrin, alpha E, epithelial-associated
  • HML-1 antigen
  • antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide
  • integrin alpha-IEL
  • mucosal lymphocyte 1 antigen
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