Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1; alpha Polypeptide) (ITGAE) antibody (FITC)

Antigen: Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1; alpha Polypeptide) (ITGAE)

Synonyms: CD103, HUMINAE, MGC141996, aM290, alpha-E1, MGC183601, A530055J10, alpha-M290

Clonality: Monoclonal (Ber-ACT8)

Host: Mouse

Reactivity: Human, Primate

Conjugate: FITC

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN810081

Additional Information

Alternative name: CD103

Gene ID: 3682

Immunogen: HTLV-1 induced human T cell line MAPS16

Isotype: IgG1

Clone: Ber-ACT8

Description: CD Antigens & MHC (Veterinary), CD and Related Antigens (Human)

Specificity: The mouse monoclonal antibody Ber-ACT8 recognizes CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes. HLDA V, WS Code A067

Application Details

Buffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Storage: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

Research Area: CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only

Publications

Product: French, Cresswell, Wong et al.: "T cell adhesion and cytolysis of pancreatic cancer cells: a role for E-cadherin in immunotherapy?" in: British journal of cancer, Vol. 87, Issue 9, pp. 1034-41, 2002 (PubMed).

Brandes, Willimann, Lang et al.: "Flexible migration program regulates gamma delta T-cell involvement in humoral immunity." in: Blood, Vol. 102, Issue 10, pp. 3693-701, 2003 (PubMed).

Poles, Barsoum, Yu et al.: "Human immunodeficiency virus type 1 induces persistent changes in mucosal and blood gammadelta T cells despite suppressive therapy." in: Journal of virology, Vol. 77, Issue 19, pp. 10456-67, 2003 (PubMed).

León, Roy: "Isolation of human small bowel intraepithelial lymphocytes by annexin V-coated magnetic beads." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 84, Issue 6, pp. 804-9, 2004 (PubMed).

Sigmundsdottir, Johnston, Gudjonsson et al.: "Methotrexate markedly reduces the expression of vascular E-selectin, cutaneous lymphocyte-associated antigen and the numbers of mononuclear leucocytes in psoriatic skin." in: Experimental dermatology, Vol. 13, Issue 7, pp. 426-34, 2004 (PubMed).

Cardoso, Garlet, Moreira et al.: "Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis." in: Journal of leukocyte biology, Vol. 84, Issue 1, pp. 311-8, 2008 (PubMed).

Kost, Holden, Mann: "Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis." in: Cytometry. Part B, Clinical cytometry, Vol. 74, Issue 5, pp. 282-6, 2008 (PubMed).

Jaensson, Uronen-Hansson, Pabst et al.: "Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans." in: The Journal of experimental medicine, Vol. 205, Issue 9, pp. 2139-49, 2008 (PubMed).

Zhang, Bertucci, Ramsey-Goldman et al.: "Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 10, pp. 6346-58, 2009 (PubMed).