This CSNK2A1/CK II alpha antibody is un-conjugated
Application
Western Blotting (WB)
Specificity
The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.
Purification
Affinity purified
Immunogen
Peptide sequence around phosphorylation site of pThr360, pSer362 (V-P-T (p) -P-S (p) -P-L) derived from Human CK2a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.