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Keratin 19 (KRT19) antibody

Antigen

Keratin 19 (KRT19)

Synonyms K19, CK19, K1CS, MGC15366, EndoC, Krt1-19, AI663979, Krt-1.19, MGC25344, Ka19, MGC124534, MGC156553, k19, ck19, k1cs, krt9, krt15, MGC76282, KRT19, GK-19, MGC83069, LOC514812, MGC154386, DKFZp469N0613
Clonality Monoclonal (BA-17)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
3 references available
Catalog no. ABIN94288
Quantity 0.1 mg  (1 mg/ml)  (Variants)
Price 304.92 $   Plus shipping costs $45.00
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Additional Information

Alternative name Cytokeratin 19
Immunogen Mammary organoids.
Isotype IgG1
Clone BA-17
Description Cytokeratins are a subfamily of intermediate filaments and characterized by remarkablebiochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20different polypeptides, molecular weight between 40 kDa and 68 kDa. The individualcytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidiccytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Specificity The antibody BA-17 reacts with cytokeratin 19 (40 kDa) in human tissue. Cytokeratin 19 isnot expressed in hepatocytes, it is often co-expressed with cytokeratin 7.

Application Details

Concentration 1 mg/ml
Purity > 95% (by SDS-PAGE)
Purification Purified from rabbit serum by protein-A afinity chromatography
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
Research Area Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
Restrictions For Research Use only

Publications

Bartek, Taylor-Papadimitriou, Miller et al.: "Patterns of expression of keratin 19 as detected with monoclonal antibodies in human breast tissues and tumours." in: International journal of cancer. Journal international du cancer, Vol. 36, Issue 3, pp. 299-306, 1985 (PubMed).

Bartek, Durban, Hallowes et al.: "A subclass of luminal epithelial cells in the human mammary gland, defined by antibodies to cytokeratins." in: Journal of cell science, Vol. 75, pp. 17-33, 1985 (PubMed).

Lewis, Klimstra, Varmus: "The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer." in: Genes & development, Vol. 17, Issue 24, pp. 3127-38, 2003 (PubMed).

Alternatives

Alternatives for antigen "Keratin 19 (KRT19)", type "Antibodies"
Hosts Mouse (125), Rabbit (83), Guinea Pig (3), Sheep (1)
Reactivities Human (187), Rat (Rattus) (39), Mouse (Murine) (36), Cow (Bovine) (23), Dog (Canine) (22), Chicken (21), Pig (Porcine) (19), Horse (Equine) (18), Xenopus laevis (3), Rabbit (2), Zebrafish (Danio rerio) (2), Amphibian (1), Cat (Feline) (1), Fish (1), Guinea Pig (1), Monkey (1)
Applications Western Blotting (WB) (150), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (101), ELISA (88), Immunohistochemistry (IHC) (72), Immunofluorescence (IF) (59), Immunocytochemistry (ICC) (26), Immunoprecipitation (IP) (23), Immunohistochemistry (Fixed) (IHC (fx)) (18), Flow Cytometry (FACS) (17), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (5), Dot Blot (Dot) (2), Immunoassay (IA) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (12), FITC (2), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (10), AA 312-335 (4), AA 80-400 (4), Internal Region (3), AA 21-40 (2), AA 311-335 (2), C-Term,AA 379-392 (2), N-Term (2), Ser46 (2), pSer46 (2), AA 352-368 (1), Center (1)