Adenylate Cyclase 2 (Brain) (ADCY2) (AA 458-489), (Middle Region) antibody

Details for Product No. ABIN950278
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Antigen
Synonyms AC2, HBAC2, mKIAA1060, ADCY2
Epitope
AA 458-489, Middle Region
(2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(30), (13), (13), (12), (12), (12)
Host
Rabbit
(27), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(20), (11), (10), (6), (2), (2), (1), (1), (1)
Pubmed 5 references available
Catalog no. ABIN950278
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human ADCY2
Specificity This antibody reacts to Adenylate cyclase type 2.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name Adenylate cyclase type 2
Background This gene encodes a member of the family of adenylate cyclases, which are membrane- associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
Alternate names: ADCY2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, KIAA1060
Gene ID 108
NCBI Accession NP_065433
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hanna, Kruskal, Ezekowitz et al.: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).

Sunahara, Taussig: "Isoforms of mammalian adenylyl cyclase: multiplicities of signaling." in: Molecular interventions, Vol. 2, Issue 3, pp. 168-84, 2004 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Need, Keefe, Ge et al.: "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." in: European journal of human genetics : EJHG, Vol. 17, Issue 7, pp. 946-57, 2009 (PubMed).

Halls, Cooper: "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." in: The EMBO journal, Vol. 29, Issue 16, pp. 2772-87, 2010 (PubMed).

Hosts (27), (3)
Reactivities (30), (13), (13), (12), (12), (12)
Applications (20), (11), (10), (6), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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