ADCY2 antibody (Middle Region)

Catalog No. ABIN2783791

The Rabbit Polyclonal anti-ADCY2 antibody (ABIN2783791) specifically detects ADCY2 in WB. The antibody is reactive with Human, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for ADCY2 antibody (Middle Region) (ABIN2783791)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADCY2 Antibody

Binding Specificity: Middle Region

Purpose: ADCY2 Antibody - middle region

Sequence: FLSDSEETIP PTANTTNTSF SASNNQVAIL RAQNLFFLPY FIYSCILGLI

Predicted Reactivity: Cow: 79%, Dog: 86%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against ADCY2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADCY2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49526-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: ADCY2

Background:

Background Information: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Gene Name: Adenylate cyclase 2 (brain)

Alternative Symbols: AC2, HBAC2

Protein Name: Adenylate cyclase type 2

Molecular Weight: 123kDa

Gene ID: 108

NCBI Accession: NP_065433

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma