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Details for Product No. ABIN951482

CES2 (AA 343-373), (Middle Region) antibody

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Antigen
Synonyms iCE, CE-2, PCE-2, CES2A1, Ces2, ces2A3
Epitope
»Alternatives AA 343-373, Middle Region
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN951482
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 343-373 amino acids from the Central region of human CES2
Specificity This antibody reacts to CES2.
Purification Affinity chromatography on Protein A
Alternative Name CES2 / ICE
Background CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood- brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
Alternate names: CE-2, Carboxylesterase 2, hCE-2
Gene ID 8824
NCBI Accession NP_003860
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Howard, Hsu, Grzywacz et al.: "Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE." in: Environmental health perspectives, Vol. 118, Issue 10, pp. 1395-9, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hatfield, Tsurkan, Hyatt et al.: "Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin." in: British journal of pharmacology, Vol. 160, Issue 8, pp. 1916-28, 2010 (PubMed).

Alternatives for antigen "CES2", type "Antibodies"
Hosts (31), (11), (2)
Reactivities (33), (8), (4), (3)
Applications (43), (24), (15), (5), (4), (3), (3), (3), (3), (2), (1)
Conjugates (2)
Epitopes (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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