CES2 Products
(Carboxylesterase 2 (CES2))
Categories
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010].
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Featured CES2 Categories
CES2 Antibodies
High quality antibodies with extensive validation data.
CES2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CES2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CES2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (2)
- (6)
Cat. No.
ABIN654618
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (5)
Cat. No.
ABIN563817
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Guinea Pig, Human, Mouse, Rat
Application
WB, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN2775271
Quantity
100 μL
Datasheet
Datasheet
Recommended CES2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999583
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954570
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882308
Quantity
96 tests
Datasheet
Datasheet
Recommended CES2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122138
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349174
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1349176
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CES2 products
: "Comprehensive and comparative exploration of the Atp7b-/- mouse plasma proteome." in: Metallomics : integrated biometal science, Vol. 12, Issue 2, pp. 249-258, (2021) (PubMed).: "Measuring human carboxylesterase 2 activity in pancreatic cancer patient-derived xenografts using a ratiometric fluorescent chemosensor." in: Chemical science, Vol. 10, Issue 36, pp. 8428-8437, (2019) (PubMed).
: "Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 44, Issue 7, pp. 959-66, (2016) (PubMed).
: "Fluoxetine reduces CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-13, (2015) (PubMed).
: "Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1?/Stra13 pathway." in: Xenobiotica; the fate of foreign compounds in biological systems, pp. 1-12, (2015) (PubMed).
: "Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 5, pp. 1159-68, (2013) (PubMed).
: "Clinical implications of CES2 RNA expression in neuroblastoma." in: Journal of pediatric surgery, Vol. 48, Issue 3, pp. 502-9, (2013) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity." in: The Journal of pharmacology and experimental therapeutics, Vol. 340, Issue 2, pp. 422-32, (2012) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyms and alternative names related to CES2
carboxylesterase 2 (CES2), carboxylesterase 2 (Ces2), liver carboxylesterase 2 (LOC100343300), cocaine esterase (LOC100734360), carboxylesterase 2 (intestine, liver) (ces2), CE-2, ce-2, Ces2, CES2A1, ces2a1, iCE, im:6908784, PCE-2, pce-2, si:dkey-38l12.2, zgc:153863Protein level used designations for CES2
- carboxylesterase 2 (intestine, liver)
- cocaine esterase
- hCE-2
- intestinal carboxylesterase; liver carboxylesterase-2
- methylumbelliferyl-acetate deacetylase 2
- liver carboxylesterase 2
- carboxylesterase 2
- carboxylesterase 2-like
- carboxylesterase 5A
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