Dullard Homolog (Xenopus Laevis) (DULLARD) (AA 138-168), (Middle Region) antibody

Details for Product No. ABIN951994
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Antigen
Synonyms dullard, dullard-a, net56, DULLARD, HSA011916, NET56, 2610507E10Rik, Dullard, ctdnep1, dullard-b, im:7137489, wu:fi48e07, zgc:92207
Epitope
AA 138-168, Middle Region
(8), (7), (1)
Reactivity
Human
(31), (15), (15), (13), (13), (1), (1)
Host
Rabbit
(31)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(22), (14), (14), (10), (7), (4)
Pubmed 4 references available
Quantity 0.4 mL
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Catalog No. ABIN951994
357.50 $
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Immunogen KLH conjugated synthetic peptide between 138-168 amino acids from the Central region of human DULLARD
Specificity This antibody recognizes Human DULLARD (Center).
Purification Affinity Chromatography on Protein A
Alternative Name DULLARD
Background Serine/threonine phosphatase which may be required for proper nuclear membrane morphology. Involved in LPIN1 dephosphorylation. May antagonize BMP signaling.
Alternate names: CTD nuclear envelope phosphatase 1, CTDNEP1, Serine/threonine-protein phosphatase dullard
Molecular Weight 28377 Da
Gene ID 23399
NCBI Accession NP_001137247
Research Area Neurology
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Satow, Chan, Asashima: "Molecular cloning and characterization of dullard: a novel gene required for neural development." in: Biochemical and biophysical research communications, Vol. 295, Issue 1, pp. 85-91, 2002 (PubMed).

Satow, Kurisaki, Chan et al.: "Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction." in: Developmental cell, Vol. 11, Issue 6, pp. 763-74, 2006 (PubMed).

Zhang, Kim, Genoud et al.: "Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1." in: Molecular cell, Vol. 24, Issue 5, pp. 759-70, 2006 (PubMed).

Kim, Gentry, Harris et al.: "A conserved phosphatase cascade that regulates nuclear membrane biogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 16, pp. 6596-601, 2007 (PubMed).

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