EIF2B1 antibody (Middle Region)

Catalog No. ABIN952043

Product Details anti-EIF2B1 Antibody

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Binding Specificity: AA 135-163, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibdoy reacts to EIF2B1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human EIF2B1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Alternative Name: EIF2B1 / EIF2BA (EIF2B1 Products)

Synonyms: DDBDRAFT_0219393 antibody, DDBDRAFT_0231375 antibody, DDB_0219393 antibody, DDB_0231375 antibody, 26kDa antibody, D5Ertd406e antibody, EIF2B antibody, EIF2BA antibody, eIF-2a antibody, translation initiation factor eIF-2B alpha subunit antibody, hypothetical protein antibody, Translation initiation factor eIF-2B subunit alpha antibody, eukaryotic translation initiation factor 2B subunit alpha antibody, eukaryotic translation initiation factor 2B, subunit 1 (alpha) antibody, eIF2b1 antibody, PGTG_05021 antibody, ei2ba antibody, eif2b1 antibody, Eif2b1 antibody, EIF2B1 antibody

Background: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.Synonyms: Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha

Molecular Weight: 33712 Da

Gene ID: 1967

NCBI Accession: NP_001405

Pathways: Methionine Biosynthetic Process