Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) (AA 135-163), (Middle Region) antibody

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Antigen
Synonyms EIF2B, EIF2BA, eIF-2a, 26kDa, D5Ertd406e, DDBDRAFT_0219393, DDBDRAFT_0231375, DDB_0219393, DDB_0231375
Epitope
AA 135-163, Middle Region
(2), (2), (2), (1), (1)
Reactivity
Human
(10), (4), (3), (1)
Host
Rabbit
(9), (2)
Clonality
Polyclonal
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(11), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN952043
Quantity 0.4 mL
Price
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Immunogen KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human EIF2B1
Specificity This antibdoy reacts to EIF2B1.
Purification Affinity chromatography on Protein A
Alternative Name EIF2B1 / EIF2BA
Background This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Alternate names: Translation initiation factor eIF-2B subunit alpha, eIF-2B GDP-GTP exchange factor subunit alpha
Gene ID 1967
NCBI Accession NP_001405
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hiyama, Ito, Imataka et al.: "Crystal structure of the alpha subunit of human translation initiation factor 2B." in: Journal of molecular biology, Vol. 392, Issue 4, pp. 937-51, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hosts (9), (2)
Reactivities (10), (4), (3), (1)
Applications (11), (2), (2), (2), (1), (1), (1), (1)
Epitopes (2), (2), (2), (1), (1)
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