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High Mobility Group Box 3 (HMGB3) (AA 49-79), (Middle Region) antibody

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Synonyms hmgb3, MGC54022, Xhmgb3, MGC88931, HMGB3, HMG-1, HMG2a, HMG4, HMGB1, HMG-2a, HMG-4, HMG2A, Hmg2a, Hmg4, RGD1564407, fa19b06, fj43d02, wu:fa19b06, wu:fj43d02, zgc:112073
AA 49-79, Middle Region
(18), (16), (15), (11), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1)
(67), (17), (10), (7), (6), (4), (2), (1), (1), (1), (1), (1), (1)
(48), (15), (5), (1)
(3), (3), (3), (3), (3), (3)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(65), (34), (11), (7), (3), (2), (1), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 49-79 amino acids from the Central region of human HMGB3
Isotype Ig
Specificity This antibody recognizes Human HMGB3 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HMGB3 (HMGB3 Antibody Abstract)
Background HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291], Nemeth et al., 2006 [PubMed 16945912]).Synonyms: HMG-2a, HMG-4, HMG2A, HMG4, HMGB-3, High mobility group protein 2a, High mobility group protein 4, High mobility group protein B3
Molecular Weight 22980 Da
Gene ID 3149
NCBI Accession NP_005333
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-High Mobility Group Box 3 (HMGB3) (AA 49-79), (Middle Region) antibody (ABIN952762) Western blot analysis of HMGB3 Antibody (Center) in NCI-H292 cell line lysates (35ug/...
Background publications Nemeth, Kirby, Bodine: "Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 37, pp. 13783-8, 2006 (PubMed).

Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Vaccari, Beltrame, Ferrari et al.: "Hmg4, a new member of the Hmg1/2 gene family." in: Genomics, Vol. 49, Issue 2, pp. 247-52, 1998 (PubMed).

Catalog No. ABIN952762
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