IL-10 antibody (Middle Region)
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- Target See all IL-10 (IL10) Antibodies
- IL-10 (IL10) (Interleukin 10 (IL10))
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Binding Specificity
- AA 33-62, Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-10 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects human IL10.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human
- Purification
- Purified through a protein A column; followed by peptide affinity purification.
- Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the center region (between 33-62aa) of human IL10.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IL10 Primary Antibody
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anti-Interleukin 10 (IL10) (AA 19-178) antibody
IL10 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 10 (IL10) (AA 101-178) antibodyIL10 Reactivity: Human, Mouse, Rat, Rabbit WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Interleukin 10 (IL10) (AA 19-178) antibodyIL10 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 10 (IL10) antibodyIL10 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Pig, Dog, Monkey, Chicken, Sheep, Goat, Avian, Cat, Donkey, Guinea Pig, Hamster WB Host: Goat Polyclonal unconjugated
anti-Interleukin 10 (IL10) antibodyMicroarray verified IL10 Reactivity: Human, Mouse IHC Host: Mouse Monoclonal MAB971550 unconjugated
anti-Interleukin 10 (IL10) antibodyMicroarray verified IL10 Reactivity: Human, Mouse IHC Host: Mouse Monoclonal MAB312926 unconjugated
anti-Interleukin 10 (IL10) antibodyIL10 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Interleukin 10 (IL10) (AA 27-53) antibodyIL10 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Interleukin 10 (IL10) (AA 1-178) antibodyIL10 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Interleukin 10 (IL10) (AA 1-178) antibodyIL10 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C5 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Alternative Name
- Interleukin-10 / IL10 (IL10 Products)
- Background
- Interleukin-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.Synonyms: CSIF, Cytokine synthesis inhibitory factor, IL-10, TGIF
- Gene ID
- 3586
- NCBI Accession
- NP_000563
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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