Lactate Dehydrogenase A (LDHA) (AA 161-190), (Middle Region) antibody

Details for Product No. ABIN953153
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Antigen
Synonyms ldh-h, ldha, ldha-B, ldhbb, trg-5, GSD11, LDH1, LDHM, LDH-M, Ldh1, Ldhm, l7R2, LDH-A, gsd11, ldh-m, ldh1, ldhm, pig19, ldha1, ldhab, LDHC
Epitope
AA 161-190, Middle Region
(15), (12), (6), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1)
Reactivity
Human
(97), (30), (21), (10), (7), (4), (1)
Host
Rabbit
(69), (42), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(11), (6), (4), (2), (2), (2), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS)
(108), (58), (37), (27), (20), (17), (10), (7), (6), (6), (4), (3), (3)
Pubmed 6 references available
Catalog no. ABIN953153
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 161~190 amino acids from the Central region of Human LDHA
Specificity This antibody recognizes Human LDHA (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name LDHA
Background LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.
Alternate names: Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, NY-REN-59, PIG19, Renal carcinoma antigen NY-REN-59
Molecular Weight 36689 Da
Gene ID 3939
NCBI Accession NP_001158887
Research Area Cancer, Metabolism, Enzymes
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Xie, Valera, Merino et al.: "LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer." in: Molecular cancer therapeutics, Vol. 8, Issue 3, pp. 626-35, 2009 (PubMed).

Zhao, Zhou, Liu et al.: "Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth." in: Oncogene, Vol. 28, Issue 42, pp. 3689-701, 2009 (PubMed).

Zhuang, Scolyer, Murali et al.: "Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 1, pp. 45-53, 2010 (PubMed).

Zhu, Feng, Li et al.: "Detecting rare variants for complex traits using family and unrelated data." in: Genetic epidemiology, Vol. 34, Issue 2, pp. 171-87, 2010 (PubMed).

Koukourakis, Giatromanolaki, Winter et al.: "Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy." in: Oncology, Vol. 77, Issue 5, pp. 285-92, 2009 (PubMed).

Hosts (69), (42), (5), (1)
Reactivities (97), (30), (21), (10), (7), (4), (1)
Applications (108), (58), (37), (27), (20), (17), (10), (7), (6), (6), (4), (3), (3)
Conjugates (11), (6), (4), (2), (2), (2), (1), (1), (1)
Epitopes (15), (12), (6), (5), (5), (4), (4), (2), (2), (2), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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