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Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody

Details for Product No. ABIN955253, Supplier: Log in to see
Antigen
  • ERIS
  • MITA
  • MPYS
  • NET23
  • STING
  • 2610307O08Rik
  • Mita
  • RGD1562552
Epitope
AA 318-348, C-Term
29
18
6
5
5
2
2
2
2
1
1
1
1
Reactivity
Human
108
32
23
Host
Rabbit
85
30
Clonality
Polyclonal
Conjugate
Un-conjugated
6
5
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
78
47
29
23
16
11
10
9
8
3
2
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173
Isotype Ig
Specificity This antibody detects TMEM173 / STING (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name TMEM173 / STING (TMEM173 Antibody Abstract)
Background Synonyms: MITA, Mediator of IRF3 activation, Stimulator of interferon genes protein, Transmembrane protein 173
Gene ID 340061
NCBI Accession NP_938023
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) TM173 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) co...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) TM173 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded breast c...
Western Blotting (WB) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) Western blot analysis of TM173 Antibody (C-term) in Jurkat cell line lysates (35 µg/l...
Background publications Sun, Li, Chen et al.: "ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 21, pp. 8653-8, 2009 (PubMed).

Zhong, Zhang, Lei et al.: "The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA." in: Immunity, Vol. 30, Issue 3, pp. 397-407, 2009 (PubMed).

Ishikawa, Barber: "STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling." in: Nature, Vol. 455, Issue 7213, pp. 674-8, 2008 (PubMed).

Jin, Waterman, Jonscher et al.: "MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals." in: Molecular and cellular biology, Vol. 28, Issue 16, pp. 5014-26, 2008 (PubMed).