Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody

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Synonyms ERIS, MITA, MPYS, NET23, STING, 2610307O08Rik, Mita, RGD1562552
AA 318-348, C-Term
(28), (17), (5), (5), (5), (2), (2), (2), (1), (1)
(123), (28), (21)
(78), (51)
(6), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(87), (49), (28), (21), (21), (20), (12), (12), (10), (7), (4), (1), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173
Isotype Ig
Specificity This antibody detects TMEM173 / STING (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name TMEM173 / STING (TMEM173 Antibody Abstract)
Background Synonyms: MITA, Mediator of IRF3 activation, Stimulator of interferon genes protein, Transmembrane protein 173
Gene ID 340061
NCBI Accession NP_938023
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) TM173 Antibody (C-term) (AP54276PU-N) flow cytometric analysis of Jurkat cells (right...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) TM173 Antibody (C-term) (AP54276PU-N) IHC analysis in formalin fixed and paraffin emb...
Western Blotting (WB) image for anti-Transmembrane Protein 173 (TMEM173) (AA 318-348), (C-Term) antibody (ABIN955253) Western blot analysis of TM173 Antibody (C-term) (AP54276PU-N) in Jurkat cell line ly...
Background publications Sun, Li, Chen et al.: "ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 21, pp. 8653-8, 2009 (PubMed).

Zhong, Zhang, Lei et al.: "The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA." in: Immunity, Vol. 30, Issue 3, pp. 397-407, 2009 (PubMed).

Ishikawa, Barber: "STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling." in: Nature, Vol. 455, Issue 7213, pp. 674-8, 2008 (PubMed).

Jin, Waterman, Jonscher et al.: "MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals." in: Molecular and cellular biology, Vol. 28, Issue 16, pp. 5014-26, 2008 (PubMed).

Catalog No. ABIN955253
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