Upstream Transcription Factor 1 (USF1) (AA 174-201), (Middle Region) antibody

Details for Product No. ABIN955484
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Antigen
Synonyms zgc:56547, USF1, uef, fchl, mltf, fchl1, mltfi, hyplip1, DKFZp469G215, usf1, bhlhb11, FCHL, FCHL1, HYPLIP1, MLTF, MLTFI, UEF, bHLHb11, rUSF1a
Epitope
AA 174-201, Middle Region
(2), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(38), (25), (21), (15), (15), (15), (13), (3), (2)
Host
Rabbit
(31), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
(29), (10), (10), (9), (3), (3), (3), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN955484
357.50 $
Plus shipping costs $45.00

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Immunogen KLH conjugated synthetic peptide between 174-201 amino acids from the Central region of human USF1
Isotype Ig
Specificity This antibody detects USF1 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name USF1
Background This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: Major late transcription factor 1, USF, Upstream stimulatory factor 1
Gene ID 7391
NCBI Accession NP_009053
Research Area Cancer, Atherosclerosis, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Background publications Naukkarinen, Nilsson, Koistinen et al.: "Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 522-9, 2009 (PubMed).

Singmann, Baumert, Herder et al.: "Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome." in: Obesity facts, Vol. 2, Issue 4, pp. 235-42, 2010 (PubMed).

Bussière, Michel, Mémet et al.: "H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression." in: Cellular microbiology, Vol. 12, Issue 8, pp. 1124-33, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Jablonski, McAteer, de Bakker et al.: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010 (PubMed).

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