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Upstream Transcription Factor 1 (USF1) (AA 174-201), (Middle Region) antibody

Details for Product No. ABIN955484, Supplier: Log in to see
Antigen
  • zgc:56547
  • USF1
  • uef
  • fchl
  • mltf
  • fchl1
  • mltfi
  • hyplip1
  • DKFZp469G215
  • usf1
  • bhlhb11
  • FCHL
  • FCHL1
  • HYPLIP1
  • MLTF
  • MLTFI
  • UEF
  • bHLHb11
  • rUSF1a
Epitope
AA 174-201, Middle Region
12
9
7
5
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
47
17
11
3
3
3
3
2
2
Host
Rabbit
37
10
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
40
22
17
11
7
1
1
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 174-201 amino acids from the Central region of human USF1
Isotype Ig
Specificity This antibody detects USF1 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name USF1 (USF1 Antibody Abstract)
Background This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: Major late transcription factor 1, USF, Upstream stimulatory factor 1
Gene ID 7391
NCBI Accession NP_009053
Research Area Cancer, Atherosclerosis, Transcription Factors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Upstream Transcription Factor 1 (USF1) (AA 174-201), (Middle Region) antibody (ABIN955484) USF1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) comp...
Immunofluorescence (IF) image for anti-Upstream Transcription Factor 1 (USF1) (AA 174-201), (Middle Region) antibody (ABIN955484) Confocal immunofluorescent analysis of USF1 Antibody (Center) with Hela cell followed...
Western Blotting (WB) image for anti-Upstream Transcription Factor 1 (USF1) (AA 174-201), (Middle Region) antibody (ABIN955484) USF1 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35 µg/la...
Background publications Jablonski, McAteer, de Bakker et al.: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Bussière, Michel, Mémet et al.: "H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression." in: Cellular microbiology, Vol. 12, Issue 8, pp. 1124-33, 2010 (PubMed).

Singmann, Baumert, Herder et al.: "Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome." in: Obesity facts, Vol. 2, Issue 4, pp. 235-42, 2010 (PubMed).

Naukkarinen, Nilsson, Koistinen et al.: "Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 522-9, 2009 (PubMed).