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Zinc Finger, MYND-Type Containing 10 (ZMYND10) (AA 328-356), (Middle Region) antibody

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Synonyms MGC134474, MGC98297, Blu, BLU, FLU
AA 328-356, Middle Region
(17), (15), (15), (13), (11), (3), (3), (2), (2), (2), (1), (1), (1), (1)
(59), (6), (4)
(50), (7), (2)
(4), (4), (4), (4), (4), (4)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (41), (32), (30), (4)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 328-356 amino acids from the Central region of human ZMYND10
Isotype Ig
Specificity This antibody detects ZMYND10 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name ZMYND10
Background BLU is a candidate tumor suppressor gene, that spans 4.5 kb on 3p21.3. It encodes a 50 kd protein, which is commonly found in transcription repressors. It is suspected that BLU has a function in cell cycle progression. BLU is a stress-responsive gene regulated by E2F.12 It is commonly found to be downregulated in non-small cell lung cancer, esophagus squamous cell carcinoma and nasopharyngeal carcinoma (NPC).Synonyms: BLU, BLu protein, LUCA12.4, Zinc finger MYND domain-containing protein 10
Gene ID 51364
NCBI Accession NP_056980
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Zinc Finger, MYND-Type Containing 10 (ZMYND10) (AA 328-356), (Middle Region) antibody (ABIN955675) ZMYND10 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffi...
Western Blotting (WB) image for anti-Zinc Finger, MYND-Type Containing 10 (ZMYND10) (AA 328-356), (Middle Region) antibody (ABIN955675) ZMYND10 Antibody (Center) western blot analysis in CEM cell line lysates (35 µg/lane)...
Background publications Shao, Zhang, Zhang et al.: "High-resolution melting analysis of BLU methylation levels in gastric, colorectal, and pancreatic cancers." in: Cancer investigation, Vol. 28, Issue 6, pp. 642-8, 2010 (PubMed).

Lorente, Mueller, Urdangarín et al.: "RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs." in: Brain pathology (Zurich, Switzerland), Vol. 19, Issue 2, pp. 279-92, 2009 (PubMed).

Muzny, Scherer, Kaul et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).

Marsit, Kim, Liu et al.: "Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence." in: International journal of cancer. Journal international du cancer, Vol. 114, Issue 2, pp. 219-23, 2005 (PubMed).

Qiu, Tan, Loh et al.: "The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma." in: Oncogene, Vol. 23, Issue 27, pp. 4793-806, 2004 (PubMed).

Catalog No. ABIN955675
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