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Abl-Interactor 1 (ABI1) (C-Term) antibody

Details for Product No. ABIN965496
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Antigen
Synonyms
ABA INSENSITIVE 1, AtABI1, F20B18.190, F20B18_190, PROTEIN PHOSPHATASE 2C ABI1, abi1, wu:fc66g09, wu:fk56a10, zgc:73174, MGC84356, ABI1, abi-1, e3b1, nap1bp, ssh3bp, ssh3bp1, abi-2, abi2b, aip-1, ablb ... show more
ABA INSENSITIVE 1, AtABI1, F20B18.190, F20B18_190, PROTEIN PHOSPHATASE 2C ABI1, abi1, wu:fc66g09, wu:fk56a10, zgc:73174, MGC84356, ABI1, abi-1, e3b1, nap1bp, ssh3bp, ssh3bp1, abi-2, abi2b, aip-1, ablbp3, argbpia, argbpib, ssh3bp2, wu:fe48a10, zgc:153534, DKFZp469P1319, ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1, NAP1, Ssh3bp1, E3b1 show less
Epitope
C-Term
(14), (13), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(65), (31), (30), (12), (12), (1), (1)
Host
Rabbit
(63), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(48), (26), (14), (14), (11), (10), (8), (7), (6), (4)
Pubmed 6 references available
Quantity 0.1 mg
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Catalog No. ABIN965496
316.25 $
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ABI1 (Abl-interactor 1)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name ABI1
Background The ABI1 (Abl-interactor 1) may act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/ or ABL2. The ABI1 may play a role in regulation of EGF-induced Erk pathway activation. It is involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 It participates in transduction of signals from Ras to Rac.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Biesova, Piccoli, Wong: "Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth." in: Oncogene, Vol. 14, Issue 2, pp. 233-41, 1997 (PubMed).

Ziemnicka-Kotula, Xu, Gu et al.: "Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13681-92, 1998 (PubMed).

Taki, Shibuya, Taniwaki et al.: "ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23)." in: Blood, Vol. 92, Issue 4, pp. 1125-30, 1998 (PubMed).

Fan, Goff: "Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7591-601, 2000 (PubMed).

Yamamoto, Suzuki, Sakaki: "Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease." in: Gene, Vol. 271, Issue 2, pp. 159-69, 2001 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Validation Images
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