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Details for Product No. ABIN965859

CES2 (C-Term) antibody

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Antigen
Synonyms iCE, CE-2, PCE-2, CES2A1, Ces2, ces2A3
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN965859
Quantity 0.1 mg
Price
288.75 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human CES2(Carboxylesterase 2 precursor)
Purification Purified by antigen-specific affinity chromatography.
Background CES2(Carboxylesterase 2)is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. CES2 shows high catalytic efficiency for hydrolysis of 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine. CES2 is preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
Research Area Signaling, Metabolism
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Schwer, Langmann, Daig et al.: "Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver." in: Biochemical and biophysical research communications, Vol. 233, Issue 1, pp. 117-20, 1997 (PubMed).

Pindel, Kedishvili, Abraham et al.: "Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin." in: The Journal of biological chemistry, Vol. 272, Issue 23, pp. 14769-75, 1997 (PubMed).

Saito, Iida, Sekine et al.: "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population." in: Journal of human genetics, Vol. 48, Issue 5, pp. 249-70, 2003 (PubMed).

Alternatives for antigen "CES2", type "Antibodies"
Hosts (31), (11), (2)
Reactivities (33), (8), (4), (3)
Applications (44), (25), (14), (6), (4), (4), (3), (3), (3), (2), (1)
Conjugates (2)
Epitopes (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
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