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GNRHR antibody (Extracellular Domain)

GNRHR Reactivity: Human WB, ELISA, FACS, IHC (fro) Host: Mouse Monoclonal B470 unconjugated
Catalog No. ABIN966217
  • Target See all GNRHR Antibodies
    GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
    Binding Specificity
    • 29
    • 25
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-29, Extracellular Domain
    Reactivity
    • 61
    • 15
    • 13
    • 2
    • 1
    Human
    Host
    • 35
    • 27
    • 1
    Mouse
    Clonality
    • 35
    • 28
    Monoclonal
    Conjugate
    • 32
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GNRHR antibody is un-conjugated
    Application
    • 28
    • 27
    • 25
    • 23
    • 9
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts with GnrH receptors found in the anterior pituitary. GnrH functions as a stimulator of gonadotrophs to release luteinizing hormone (LH) and follicle stimulating hormone (FSH).
    Purification
    Concentrated.
    Immunogen
    BSA-conjugated peptide (amino acids1-29) of human GnrH receptor extracellular domain.
    Clone
    B470
    Isotype
    IgG1
    Top Product
    Discover our top product GNRHR Primary Antibody
  • Application Notes
    Immunohistochemistry: 1:50-1:100.
    ELISA: 1:1000-1:3000.
    Flow cytometry: 1:150-1:300.
    Western Blot 1:200-1:500.
    Staining Procedure: This antibody can be used on frozen tissue sections. The antibody may be used at a dilution of 1:50-1:100 in IHC. The optimal conditions should be determined by the individual laboratory.
    Comment

    Recommended Positive Control: Pituitary Tissue.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/ml.
    Buffer
    20 mM tris-borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing fetal bovine serum, BMC-6 carrier polysaccharides, carrier protein, pH 7.5
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Grosse, Schöneberg, Schultz, Gudermann: "Inhibition of gonadotropin-releasing hormone receptor signaling by expression of a splice variant of the human receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 11, Issue 9, pp. 1305-18, (1997) (PubMed).

    Jennes, Eyigor, Janovick, Conn: "Brain gonadotropin releasing hormone receptors: localization and regulation." in: Recent progress in hormone research, Vol. 52, pp. 475-90; discussion 490-1, (1997) (PubMed).

    Fraser, Sellar, Illingworth, Eidne: "GnRH receptor mRNA expression by in-situ hybridization in the primate pituitary and ovary." in: Molecular human reproduction, Vol. 2, Issue 2, pp. 117-21, (1997) (PubMed).

    Arora, Cheng, Catt: "Mutations of the conserved DRS motif in the second intracellular loop of the gonadotropin-releasing hormone receptor affect expression, activation, and internalization." in: Molecular endocrinology (Baltimore, Md.), Vol. 11, Issue 9, pp. 1203-12, (1997) (PubMed).

  • Target
    GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
    Alternative Name
    GnRH Receptor (GNRHR Products)
    Synonyms
    GNRHR1 antibody, GRHR antibody, HH7 antibody, LHRHR antibody, LRHR antibody, GNRHR antibody, GH1 antibody, Lhrhr antibody, GNRHR1/III antibody, GNRHR2 antibody, xgnrhr antibody, gnrhr3/ii antibody, gnrh-r antibody, gonadotropin releasing hormone receptor antibody, gonadotropin-releasing hormone receptor antibody, GNRHR antibody, Gnrhr antibody, gnrhr antibody, gnrh-r antibody
    Gene ID
    2798
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