Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GNRHR Products

(Gonadotropin-Releasing Hormone Receptor (GNRHR))
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured GNRHR Categories

GNRHR Antibodies

High quality antibodies with extensive validation data.

GNRHR ELISA Kits

Reliable ELISA kits for a wide range of species.

GNRHR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GNRHR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IHC (fro), ICC, IF (cc), IF (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN686917
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7242191
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC (fro)
Validations
  • (4)
Cat. No. ABIN966217
Quantity 0.5 mL
Datasheet Datasheet

Recommended GNRHR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967187
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967186
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967185
Quantity 96 tests
Datasheet Datasheet

Recommended GNRHR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN6964191
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330111
Quantity 2 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7394573
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our GNRHR products

Baek, Park, Park, Kim, Kim, Suh, Kim, Kim, Kim, Nam: "Androgen receptor as a prognostic biomarker and therapeutic target in uterine leiomyosarcoma." in: Journal of gynecologic oncology, Vol. 29, Issue 3, pp. e30, (2019) (PubMed).

Ciechanowska, Łapot, Paruszewska, Radawiec, Przekop et al.: "The influence of dopaminergic system inhibition on biosynthesis of gonadotrophin-releasing hormone (GnRH) and GnRH receptor in anoestrous sheep; hierarchical role of kisspeptin and RFamide-related ..." in: Reproduction, fertility, and development, (2018) (PubMed).

Park, Baek, Park, Kim, Nam: "Investigation of hormone receptor expression and its prognostic value in endometrial stromal sarcoma." in: Virchows Archiv : an international journal of pathology, Vol. 473, Issue 1, pp. 61-69, (2018) (PubMed).

López-Doval, Salgado, Lafuente: "The expression of several reproductive hormone receptors can be modified by perfluorooctane sulfonate (PFOS) in adult male rats." in: Chemosphere, Vol. 155, pp. 488-97, (2016) (PubMed).

Liu, Li, Zhu, Yu, Guo, Zhou, Zheng, Qu, Huang, Chen, Wang, Ye: "Effects of di-(2-ethylhexyl) phthalate on the hypothalamus-pituitary-ovarian axis in adult female rats." in: Reproductive toxicology (Elmsford, N.Y.), Vol. 46, pp. 141-7, (2014) (PubMed).

Benz, Le Hir, Norez, Kerbiriou, Calvez, Becq, Trouvé, Férec: "Improvement of chloride transport defect by gonadotropin-releasing hormone (GnRH) in cystic fibrosis epithelial cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88964, (2014) (PubMed).

Ko, Guo, Barengo, Naora: "Inhibition of ovarian cancer growth by a tumor-targeting peptide that binds eukaryotic translation initiation factor 4E." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4336-47, (2009) (PubMed).

Yeung, An, Cheng, Chow, Leung: "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells." in: Molecular human reproduction, Vol. 11, Issue 11, pp. 837-42, (2006) (PubMed).

Cheng, Yeung, Chow, Leung: "Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 7, pp. 1552-64, (2002) (PubMed).

Wolfahrt, Kleine, Jarry, Rossmanith: "Endogenous regulation of the GnRH receptor by GnRH in the human placenta." in: Molecular human reproduction, Vol. 7, Issue 1, pp. 89-95, (2001) (PubMed).

Synonyms and alternative names related to GNRHR

gonadotropin releasing hormone receptor (GNRHR), gonadotropin releasing hormone receptor (Gnrhr), gonadotropin releasing hormone receptor (gnrhr), gonadotropin-releasing hormone receptor (gnrh-r), GH1, gnrh-r, GNRHR, GNRHR1, GNRHR1/III, GNRHR2, gnrhr3/ii, GRHR, HH7, LHRHR, Lhrhr, LRHR, xgnrhr

Protein level used designations for GNRHR

  • gnRH receptor
  • gnRH-R
  • gonadotropin-releasing hormone (type 1) receptor 1
  • leutinizing hormone releasing horomone receptor
  • leutinizing-releasing hormone receptor
  • luliberin receptor
  • type I GnRH receptor
  • GnRH receptor
  • gonadotropin-releasing hormone receptor
  • gonadotropin releasing hormone receptor
  • growth hormone
  • luteinizing-releasing hormone receptor
  • gnoadotropin releasing hormone receptor 2
  • gonadotropin-releasing hormone II receptor
  • type 1/III gonadotropin-releasing hormone receptor hexahelical
  • type 3/II gonadotropin-releasing hormone receptor
  • pituitary GnRH receptor
  • pituitary gonadotropin-releasing hormone receptor
  • LHRH
  • luteinizing hormone-releasing hormone receptor
You are here:
Support