anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian))

Details for Product anti-ERBB2 Antibody No. ABIN966279
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Antigen
Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1, Erbb-2, Neu, c-erbB2, c-neu, mKIAA3023
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(1084), (401), (254), (10), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(913), (288), (23), (19), (5), (5)
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
(74), (60), (54), (45), (44), (42), (9), (9), (9), (9), (9), (9), (9), (9), (1)
Application
Immunohistochemistry (IHC)
(612), (451), (324), (282), (211), (209), (127), (92), (91), (66), (65), (19), (16), (10), (8), (6), (5), (3), (3), (2), (1), (1), (1), (1)
Pubmed 6 references available
Quantity 100 μg
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 877 (T-E-YP-H-A).
Specificity HER2 (Ab-877) antibody detects endogenous levels of total HER2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name HER2 (ERBB2 Antibody Abstract)
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Dittadi, Gion: "More about: prognostic importance of low c-erbB2 expression in breast tumors." in: Journal of the National Cancer Institute, Vol. 92, Issue 17, pp. 1443-4, 2000 (PubMed).

Klapper, Waterman, Sela et al.: "Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2." in: Cancer research, Vol. 60, Issue 13, pp. 3384-8, 2000 (PubMed).

Zhang, Wong-Riley: "Synthesis and degradation of cytochrome oxidase subunit mRNAs in neurons: differential bigenomic regulation by neuronal activity." in: Journal of neuroscience research, Vol. 60, Issue 3, pp. 338-44, 2000 (PubMed).

Muthuswamy, Gilman, Brugge: "Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6845-57, 2000 (PubMed).

Kwon, Bhattacharyya, Alberta et al.: "Activation of ErbB2 during wallerian degeneration of sciatic nerve." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 21, pp. 8293-9, 1997 (PubMed).

Qian, LeVea, Freeman et al.: "Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 4, pp. 1500-4, 1994 (PubMed).

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Catalog No. ABIN966279
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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