You are viewing an incomplete version of our website. Please click to reload the website as full version.

HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian))

Details for Product anti-ERBB2 Antibody No. ABIN966279, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1, Erbb-2, Neu, c-erbB2, c-neu, mKIAA3023
Alternatives
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(1242), (414), (239), (25), (14), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host
Rabbit
(986), (395), (21), (19), (5), (5)
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
(73), (62), (52), (45), (45), (41), (11), (9), (9), (8), (8), (8), (8), (8), (8), (2), (2), (1)
Application
Immunohistochemistry (IHC)
(668), (521), (335), (323), (243), (228), (142), (139), (93), (62), (24), (21), (17), (10), (6), (6), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 6 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 100 μg
Options
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 877 (T-E-YP-H-A).
Specificity HER2 (Ab-877) antibody detects endogenous levels of total HER2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name HER2 (ERBB2 Antibody Abstract)
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Dittadi, Gion: "More about: prognostic importance of low c-erbB2 expression in breast tumors." in: Journal of the National Cancer Institute, Vol. 92, Issue 17, pp. 1443-4, 2000 (PubMed).

Klapper, Waterman, Sela et al.: "Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2." in: Cancer research, Vol. 60, Issue 13, pp. 3384-8, 2000 (PubMed).

Zhang, Wong-Riley: "Synthesis and degradation of cytochrome oxidase subunit mRNAs in neurons: differential bigenomic regulation by neuronal activity." in: Journal of neuroscience research, Vol. 60, Issue 3, pp. 338-44, 2000 (PubMed).

Muthuswamy, Gilman, Brugge: "Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6845-57, 2000 (PubMed).

Kwon, Bhattacharyya, Alberta et al.: "Activation of ErbB2 during wallerian degeneration of sciatic nerve." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 21, pp. 8293-9, 1997 (PubMed).

Qian, LeVea, Freeman et al.: "Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 4, pp. 1500-4, 1994 (PubMed).

Catalog No. ABIN966279
$398.75
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)