Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibody

Details for Product No. ABIN966625
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms 2410014J02Rik, MLC-2, Mlc2, CMH10, MLC2, Mlc-2, myosin, regulatory, MLC-2v, Mlc2v, Mylpc
Reactivity
Human
(53), (17), (14), (2), (1), (1), (1), (1)
Host
Mouse
(35), (22)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1)
Application
Western Blotting (WB), ELISA
(48), (36), (8), (8), (8), (3), (3), (2)
Pubmed 2 references available
Quantity 0.1 mL
Options
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Purified recombinant fragment of MYL2 expressed in E. Coli.
Clone 7C9
Isotype IgG1
Purification Ascitic fluid
Alternative Name MYL2 (MYL2 Antibody Abstract)
Background MYL2(myosin, light chain 2, regulatory, cardiac, slow), also known as MLC-2, MLC2v. Entrez protein NP_000423. MYL2 associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. It is an hexamer of two heavy chains and four light chains that is predominantly expressed in adult cardiac ventricle muscle. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Synonyms: MLC2, CMH10, DKFZp779C0562
Molecular Weight 19kDa
Gene ID 4633
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Sachdev, Raychowdhury, Sarkar: "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 14, Issue 5, pp. 339-50, 2004 (PubMed).

Ueda, Murata-Hori, Tatsuka et al.: "Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells." in: Oncogene, Vol. 21, Issue 38, pp. 5852-60, 2002 (PubMed).

Validation Images
Catalog No. ABIN966625
385.00 $
Plus shipping costs $45.00
Quantity
Price
0.1 mL
385.00 $

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?