Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11) (N-Term) antibody

Antigen: Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11)

Synonyms: xCT, CCBR1, sut, AI451155, 9930009M05Rik, SLC7A11, DKFZp468E122

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine), Rat (Rattus)

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN967037

Additional Information

Alternative name: Slc7a11

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Slc7a11 (Cystine/glutamate transporter)

Description: Slc7a11 (Cystine/glutamate transporter) is a sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. Slc7a11 is disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc. Slc7a11 is a multi-pass membrane protein and belongs to the amino acid-polyamine-organocation (APC) superfamily and L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Synonyms: Amino acid transport system xc- ( xCT)

Application Details

Restrictions: For Research Use only

Publications

Product: Sato, Tamba, Ishii et al.: "Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins." in: The Journal of biological chemistry, Vol. 274, Issue 17, pp. 11455-8, 1999 (PubMed).

Sasaki, Sato, Kuriyama-Matsumura et al.: "Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 44765-71, 2002 (PubMed).

Trost, English, Lemieux et al.: "The phagosomal proteome in interferon-gamma-activated macrophages." in: Immunity, Vol. 30, Issue 1, pp. 143-54, 2009 (PubMed).