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Integrin beta 3 (ITGB3) antibody

Details for Product No. ABIN967485
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Antigen
Synonyms BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, INGRB3, integrin
Reactivity
Human, Baboon, Rhesus Monkey, Cynomolgus, Cow (Bovine)
(307), (164), (80), (48), (43), (26), (26), (9), (4), (3), (1), (1), (1), (1), (1)
Host
Mouse
(172), (157), (49), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(54), (29), (22), (7), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(185), (173), (71), (66), (57), (48), (36), (34), (13), (12), (8), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN967485
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Clone VI-PL2
Isotype IgG1, kappa
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Purity Purified
Alternative Name CD61
Background Reacts with integrin beta3, a 105 kDa transmembrane glycoprotein, expressed on platelets, megakaryocytes, osteoclasts and endothelia. Integrin beta3 associates with gpIIa (CD41) to form the CD41/CD61 complex which mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the CD51/CD61 complex (vitronectin receptor). CD61 appears to bind to fibrinogen, fibronectin, vWF, vitronectin, and thrombospondin to mediate cell adhesion. This antibody is routinely tested by flow cytometric analysis.
Synonyms: Integrin beta3 Chain
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer Aqueous buffered solution.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
anti-Integrin beta 3 (ITGB3) antibody Profile of peripheral blood platelets analyzed by flow cytometry
Product cited in: Mason, André, Bensussan et al.: "CD antigens 2001." in: Tissue antigens, Vol. 58, Issue 6, pp. 425-30, 2002 (PubMed).

General Komori, Yagi, Nomura et al.: "Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts." in: Cell, Vol. 89, Issue 5, pp. 755-64, 1997 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN967485
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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