EPH Receptor B3 (EPHB3) (AA 39-212) antibody

Details for Product No. ABIN969106
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Antigen
Synonyms tck, MGC83457, EPHB3, ETK2, HEK2, TYRO6, AW456895, Cek10, Etk2, MDK5, Sek4, Tyro6, CEK10, EK10, ek3, ephb3, fc62d03, rtk3, wu:fc62d03, zek3
Epitope
AA 39-212
(23), (9), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(90), (28), (18)
Host
Mouse
(62), (33), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
(77), (46), (32), (24), (18), (10), (4), (3), (2), (2), (1)
Pubmed 4 references available
Quantity 100 μL
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Immunogen Purified recombinant fragment of EphB3 (AA 39-212) expressed in E. coli.
Clone 4A122D1
Isotype IgG2a
Purification Ascites
Alternative Name EphB3 (EPHB3 Antibody Abstract)
Background EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Gene ID 2049
HGNC 2049
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody Figure 2: Immunohistochemical analysis of paraffin-embedded human lung squamous cell ...
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody (2) Figure 3: Immunohistochemical analysis of paraffin-embedded human Adrenal tissues usi...
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibody (3) Figure 1: Western blot analysis using EphB3 mouse mAb against truncated EphB3-His rec...
Product cited in: Trivier, Ganesan: "RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 23037-43, 2002 (PubMed).

Hock, Böhme, Karn et al.: "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 17, pp. 9779-84, 1998 (PubMed).

Bergemann, Zhang, Chiang et al.: "Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube." in: Oncogene, Vol. 16, Issue 4, pp. 471-80, 1998 (PubMed).

Background publications Zhou: "The Eph family receptors and ligands." in: Pharmacology & therapeutics, Vol. 77, Issue 3, pp. 151-81, 1998 (PubMed).

Validation Images
Catalog No. ABIN969106
442.20 $
Plus shipping costs $45.00
Quantity
Price
100 μL
442.20 $

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