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GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

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Antigen
Synonyms E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07, Nrf2a, Nrf-2alpha, X-alpha1, XrpFI, e4tf1-60, e4tf1a, nft2, nrf2, nrf2a, GABPalpha, e4tf, wu:fc12d11, gabpa-A, GABPA
Epitope
»Alternatives AA 120-190
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ( )
Application
»Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN969163
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
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Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen Purified recombinant fragment of human GABPA (AA 120-190) expressed in E. Coli.
Clone
Isotype IgG1
Purification Ascites

Target Details

Application Details Handling References Alternatives back to top
Alternative Name GABPA
Background GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Synonyms: NFT2, NRF2
Molecular Weight 51kDa
Gene ID 2551
Research Area Chromatin and Nuclear Signaling, Transcription Factors

Application Details

Target Details Handling References Alternatives back to top
Application Notes Western Blotting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Format Liquid
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage 4 °C

References

Target Details Application Details Handling Alternatives back to top
Product cited in: Batchelor, Piper, de la Brousse et al.: "The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA." in: Science (New York, N.Y.), Vol. 279, Issue 5353, pp. 1037-41, 1998 (PubMed).

Sawada, Simizu, Suzuki et al.: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, 2000 (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, 2000 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA)", type "Antibodies"
Hosts (17), (11)
Reactivities (27), (6), (1), (1), (1), (1), (1), (1)
Applications (25), (17), (14), (6), (2), (1), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1), (1), (1)
Beacon
Guglhupf
Guglhupf Guglhupf Guglhupf