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Details for Product No. ABIN969163

GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

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Synonyms E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07, Nrf2a, Nrf-2alpha, X-alpha1, XrpFI, e4tf1-60, e4tf1a, nft2, nrf2, nrf2a, e4tf, wu:fc12d11, gabpa-A, GABPA
»Alternatives AA 120-190
»Alternatives Human, Mouse (Murine)
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
Pubmed 3 references available
Catalog no. ABIN969163
Quantity 100 µL
363.00 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of human GABPA (AA 120-190) expressed in E. coli.
Clone 8C1B10
Isotype IgG1
Purification Ascites
Alternative Name GABPA
Background Synonyms:
GABPA: GA binding protein transcription factor, α subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Molecular Weight 51 kDa
Gene ID 2551
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Batchelor, Piper, de la Brousse et al.: "The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA." in: Science (New York, N.Y.), Vol. 279, Issue 5353, pp. 1037-41, 1998 (PubMed).

Sawada, Simizu, Suzuki et al.: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, 2000 (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, 2000 (PubMed).

Alternatives for antigen "GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA)", type "Antibodies"
Hosts (27), (27)
Reactivities (53), (21), (15), (13), (13), (13), (12), (1), (1)
Applications (41), (25), (21), (15), (10), (4), (2), (2), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)