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Details for Product No. ABIN969163

GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

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Antigen
Synonyms E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07, Nrf2a, Nrf-2alpha, X-alpha1, XrpFI, e4tf1-60, e4tf1a, nft2, nrf2, nrf2a, e4tf, wu:fc12d11, gabpa-A, GABPA
Epitope
»Alternatives AA 120-190
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
Pubmed 3 references available
Catalog no. ABIN969163
Quantity 100 µL
Price
363.00 $   Plus shipping costs $45.00
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anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody

anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (2)

anti-GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA) (AA 120-190) antibody (3)

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen Purified recombinant fragment of human GABPA (AA 120-190) expressed in E. coli.
Clone 8C1B10
Isotype IgG1
Purification Ascites

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name GABPA
Background Synonyms:
NFT2, NRF2
GABPA: GA binding protein transcription factor, α subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Molecular Weight 51 kDa
Gene ID 2551
Research Area Chromatin and Nuclear Signaling, Transcription Factors

Application Details

Target Details Handling Images References Alternatives back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Target Details Application Details Images References Alternatives back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References

Target Details Application Details Handling Images Alternatives back to top
Product cited in: Batchelor, Piper, de la Brousse et al.: "The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA." in: Science (New York, N.Y.), Vol. 279, Issue 5353, pp. 1037-41, 1998 (PubMed).

Sawada, Simizu, Suzuki et al.: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, 2000 (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, 2000 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA)", type "Antibodies"
Hosts (27), (27)
Reactivities (53), (21), (15), (13), (13), (13), (12), (1), (1)
Applications (41), (25), (21), (15), (10), (4), (2), (2), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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