GABPA antibody (Internal Region)

Catalog No. ABIN2855427

Product Details anti-GABPA Antibody

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABPA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Cross-Reactivity: Rhesus Monkey

Cross-Reactivity (Details): Rhesus Monkey (100 %)

Characteristics: Rabbit Polyclonal antibody to GABPA (GA binding protein transcription factor, alpha subunit 60 kDa)
GABPA antibody [N2C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GABPA. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Alternative Name: GABPA (GABPA Products)

Synonyms: gabpa-A antibody, XrpFI antibody, X-alpha1 antibody, GABPA antibody, nft2 antibody, nrf2 antibody, nrf2a antibody, e4tf1a antibody, e4tf1-60 antibody, Nrf-2alpha antibody, Nrf2a antibody, E4TF1-60 antibody, E4TF1A antibody, NFT2 antibody, NRF2 antibody, NRF2A antibody, RCH04A07 antibody, GABPalpha antibody, e4tf antibody, wu:fc12d11 antibody, GA binding protein transcription factor alpha subunit S homeolog antibody, GA binding protein transcription factor alpha subunit antibody, GA binding protein transcription factor, alpha subunit antibody, GA binding protein transcription factor alpha subunit L homeolog antibody, GA repeat binding protein, alpha antibody, gabpa.S antibody, GABPA antibody, gabpa antibody, Gabpa antibody, gabpa.L antibody

Background: This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.

Cellular Localization: Nucleus

Molecular Weight: 51 kDa

Gene ID: 2551

Pathways: Myometrial Relaxation and Contraction